Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cells

When expressed in tobacco cells, the catalytic subunit of the dimeric ribosome inactivating protein, ricin, is first inserted into the endoplasmic reticulum (ER) and then degraded in a manner that can be partially inhibited by the proteasome inhibitor clasto-lactacystin β-lactone. Consistent with th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Di Cola, Alessandra, Frigerio, Lorenzo, Lord, J. Michael, Ceriotti, Aldo, Roberts, Lynne M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11734657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251386098
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