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The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl(–) concentration

Activation of the CFTR Cl(–) channel inhibits epithelial Na(+) channels (ENaC), according to studies on epithelial cells and overexpressing recombinant cells. Here we demonstrate that ENaC is inhibited during stimulation of the cystic fibrosis transmembrance conductance regulator (CFTR) in Xenopus o...

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Bibliografische gegevens
Hoofdauteurs: König, Jens, Schreiber, Rainer, Voelcker, Thilo, Mall, Marcus, Kunzelmann, Karl
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084131/
https://ncbi.nlm.nih.gov/pubmed/11606421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve232
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