The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl(–) concentration

Activation of the CFTR Cl(–) channel inhibits epithelial Na(+) channels (ENaC), according to studies on epithelial cells and overexpressing recombinant cells. Here we demonstrate that ENaC is inhibited during stimulation of the cystic fibrosis transmembrance conductance regulator (CFTR) in Xenopus o...

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Détails bibliographiques
Auteurs principaux: König, Jens, Schreiber, Rainer, Voelcker, Thilo, Mall, Marcus, Kunzelmann, Karl
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2001
Sujets:
Scientific Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084131/
https://ncbi.nlm.nih.gov/pubmed/11606421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve232
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