The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl(–) concentration

Activation of the CFTR Cl(–) channel inhibits epithelial Na(+) channels (ENaC), according to studies on epithelial cells and overexpressing recombinant cells. Here we demonstrate that ENaC is inhibited during stimulation of the cystic fibrosis transmembrance conductance regulator (CFTR) in Xenopus o...

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Detalles Bibliográficos
Main Authors: König, Jens, Schreiber, Rainer, Voelcker, Thilo, Mall, Marcus, Kunzelmann, Karl
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
Assuntos:
Scientific Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084131/
https://ncbi.nlm.nih.gov/pubmed/11606421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve232
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