The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na(+) channel
The cystic-fibrosis transmembrane conductance regulator (CFTR) functions as a cAMP-regulated Cl(−) channel and as a regulator of other membrane conductances. cAMP-dependent activation of CFTR inhibits epithelial Na(+) channels (ENaC). The specificity of interaction between CFTR and ENaC was examined...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21860/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10220462/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.9.5310 |
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