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The first-nucleotide binding domain of the cystic-fibrosis transmembrane conductance regulator is important for inhibition of the epithelial Na(+) channel
The cystic-fibrosis transmembrane conductance regulator (CFTR) functions as a cAMP-regulated Cl(−) channel and as a regulator of other membrane conductances. cAMP-dependent activation of CFTR inhibits epithelial Na(+) channels (ENaC). The specificity of interaction between CFTR and ENaC was examined...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21860/ https://ncbi.nlm.nih.gov/pubmed/10220462 |
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