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The cystic fibrosis transmembrane conductance regulator (CFTR) inhibits ENaC through an increase in the intracellular Cl(–) concentration

Activation of the CFTR Cl(–) channel inhibits epithelial Na(+) channels (ENaC), according to studies on epithelial cells and overexpressing recombinant cells. Here we demonstrate that ENaC is inhibited during stimulation of the cystic fibrosis transmembrance conductance regulator (CFTR) in Xenopus o...

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Hlavní autoři: König, Jens, Schreiber, Rainer, Voelcker, Thilo, Mall, Marcus, Kunzelmann, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084131/
https://ncbi.nlm.nih.gov/pubmed/11606421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve232
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