Mitochondrial dysfunction and cell senescence — skin deep into mammalian aging

Por Passos, Joao F., von Zglinicki, Thomas
Publicado em 2012

Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction: application of a simple dynamic model

Por Miwa, Satomi, Lawless, Conor, von Zglinicki, Thomas
Publicado em 2008

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?

Por Passos, João F., Saretzki, Gabriele, von Zglinicki, Thomas
Publicado em 2007

Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage.

Por Kurz, Tino, Leake, Alan, Von Zglinicki, Thomas, Brunk, Ulf T
Publicado em 2004

Male mice retain a metabolic memory of improved glucose tolerance induced during adult onset, short-term dietary restriction

Por Cameron, Kerry M, Miwa, Satomi, Walker, Cornelia, von Zglinicki, Thomas
Publicado em 2012

Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

Por Korolchuk, Viktor I., Miwa, Satomi, Carroll, Bernadette, von Zglinicki, Thomas
Publicado no EBioMedicine (2017)

Cellular senescence: unravelling complexity

Por Passos, João F., Simillion, Cedric, Hallinan, Jennifer, Wipat, Anil, von Zglinicki, Thomas
Publicado em 2009

Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H(2)O(2) release assays

Por Miwa, Satomi, Treumann, Achim, Bell, Amy, Vistoli, Giulio, Nelson, Glyn, Hay, Sam, von Zglinicki, Thomas
Publicado no Free Radic Biol Med (2016)

A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations

Por Lawless, Conor, Jurk, Diana, Gillespie, Colin S., Shanley, Daryl, Saretzki, Gabriele, von Zglinicki, Thomas, Passos, João F.
Publicado em 2012

A senescent cell bystander effect: senescence-induced senescence

Por Nelson, Glyn, Wordsworth, James, Wang, Chunfang, Jurk, Diana, Lawless, Conor, Martin-Ruiz, Carmen, von Zglinicki, Thomas
Publicado em 2012

Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

Por Miwa, Satomi, Czapiewski, Rafal, Wan, Tengfei, Bell, Amy, Hill, Kirsten N., von Zglinicki, Thomas, Saretzki, Gabriele
Publicado no Aging (Albany NY) (2016)

Childhood Growth, IQ and Education as Predictors of White Blood Cell Telomere Length at Age 49–51 Years: The Newcastle Thousand Families Study

Por Pearce, Mark S., Mann, Kay D., Martin-Ruiz, Carmen, Parker, Louise, White, Martin, von Zglinicki, Thomas, Adams, Jean
Publicado em 2012

Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

Por Miwa, Satomi, Jow, Howsun, Baty, Karen, Johnson, Amy, Czapiewski, Rafal, Saretzki, Gabriele, Treumann, Achim, von Zglinicki, Thomas
Publicado em 2014

Age-related frailty and its association with biological markers of ageing

Por Mitnitski, Arnold, Collerton, Joanna, Martin-Ruiz, Carmen, Jagger, Carol, von Zglinicki, Thomas, Rockwood, Kenneth, Kirkwood, Thomas B. L.
Publicado no BMC Med (2015)

CMV seropositivity and T‐cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study

Por Spyridopoulos, Ioakim, Martin‐Ruiz, Carmen, Hilkens, Catharien, Yadegarfar, Mohammad E., Isaacs, John, Jagger, Carol, Kirkwood, Tom, von Zglinicki, Thomas
Publicado no Aging Cell (2015)

Telomere length and anaemia in old age: results from the Newcastle 85-plus Study* and the Leiden 85-plus Study

Por Den Elzen, Wendy P. J., Martin-Ruiz, Carmen, von Zglinicki, Thomas, Westendorp, Rudi G. J., Kirkwood, Thomas B. L., Gussekloo, Jacobijn
Publicado em 2011

Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions

Por Dalle Pezze, Piero, Nelson, Glyn, Otten, Elsje G., Korolchuk, Viktor I., Kirkwood, Thomas B. L., von Zglinicki, Thomas, Shanley, Daryl P.
Publicado em 2014

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

Por Arai, Yasumichi, Martin-Ruiz, Carmen M., Takayama, Michiyo, Abe, Yukiko, Takebayashi, Toru, Koyasu, Shigeo, Suematsu, Makoto, Hirose, Nobuyoshi, von Zglinicki, Thomas
Publicado no EBioMedicine (2015)

The Newcastle 85+ study: biological, clinical and psychosocial factors associated with healthy ageing: study protocol

Por Martin-Ruiz Carmen, James Oliver, Jagger Carol, Eccles Martin, Bond John, Barrass Karen, Collerton Joanna, Robinson Louise, von Zglinicki Thomas, Kirkwood Tom
Publicado em 2007-06-01

The Newcastle 85+ study: biological, clinical and psychosocial factors associated with healthy ageing: study protocol

Por Collerton, Joanna, Barrass, Karen, Bond, John, Eccles, Martin, Jagger, Carol, James, Oliver, Martin-Ruiz, Carmen, Robinson, Louise, von Zglinicki, Thomas, Kirkwood, Tom
Publicado em 2007