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Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?

Cell senescence is increasingly recognized as a major contributor to the loss of health and fitness associated with aging. Senescent cells accumulate dysfunctional mitochondria; oxidative phosphorylation efficiency is decreased and reactive oxygen species production is increased. In this review we w...

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Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Korolchuk, Viktor I., Miwa, Satomi, Carroll, Bernadette, von Zglinicki, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514379/
https://ncbi.nlm.nih.gov/pubmed/28330601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.020
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