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The mTORC1-autophagy pathway is a target for senescent cell elimination

Cellular senescence has recently been established as a key driver of organismal ageing. The state of senescence is controlled by extensive rewiring of signalling pathways, at the heart of which lies the mammalian Target of Rapamycin Complex I (mTORC1). Here we discuss recent publications aiming to e...

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Bibliografiska uppgifter
I publikationen:Biogerontology
Huvudupphovsmän: Kucheryavenko, Olena, Nelson, Glyn, von Zglinicki, Thomas, Korolchuk, Viktor I., Carroll, Bernadette
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Netherlands 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535413/
https://ncbi.nlm.nih.gov/pubmed/30798505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-019-09802-9
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