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The senescent bystander effect is caused by ROS-activated NF-κB signalling

Cell senescence is an important driver of the ageing process. The accumulation of senescent cells in tissues is accelerated by stress signals from senescent cells that induce DNA damage and ultimately senescence in bystander cells. We examine here the interplay of senescence-associated mitochondrial...

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Detalhes bibliográficos
Publicado no:Mech Ageing Dev
Main Authors: Nelson, Glyn, Kucheryavenko, Olena, Wordsworth, James, von Zglinicki, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Ireland 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861994/
https://ncbi.nlm.nih.gov/pubmed/28837845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.08.005
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