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The senescent bystander effect is caused by ROS-activated NF-κB signalling

Cell senescence is an important driver of the ageing process. The accumulation of senescent cells in tissues is accelerated by stress signals from senescent cells that induce DNA damage and ultimately senescence in bystander cells. We examine here the interplay of senescence-associated mitochondrial...

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Détails bibliographiques
Publié dans:Mech Ageing Dev
Auteurs principaux: Nelson, Glyn, Kucheryavenko, Olena, Wordsworth, James, von Zglinicki, Thomas
Format: Artigo
Langue:Inglês
Publié: Elsevier Science Ireland 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861994/
https://ncbi.nlm.nih.gov/pubmed/28837845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.08.005
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