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The senescent bystander effect is caused by ROS-activated NF-κB signalling

Cell senescence is an important driver of the ageing process. The accumulation of senescent cells in tissues is accelerated by stress signals from senescent cells that induce DNA damage and ultimately senescence in bystander cells. We examine here the interplay of senescence-associated mitochondrial...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mech Ageing Dev
Hauptverfasser: Nelson, Glyn, Kucheryavenko, Olena, Wordsworth, James, von Zglinicki, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science Ireland 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861994/
https://ncbi.nlm.nih.gov/pubmed/28837845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2017.08.005
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