Comparability of PD‐L1 immunohistochemistry assays for non‐small‐cell lung cancer: a systematic review

by Koomen, Bregje M, Badrising, Sushil K, van den Heuvel, Michel M, Willems, Stefan M
Published in Histopathology (2020)

Barriers and Facilitators for Implementation of a Computerized Clinical Decision Support System in Lung Cancer Multidisciplinary Team Meetings—A Qualitative Assessment

by Klarenbeek, Sosse E., Schuurbiers-Siebers, Olga C. J., van den Heuvel, Michel M., Prokop, Mathias, Tummers, Marcia
Published in Biology (Basel) (2020)

Nivolumab in pre-treated advanced non-small cell lung cancer: long term follow up data from the Dutch expanded access program and routine clinical care

by Schouten, Robert D., Egberink, Lucie, Muller, Mirte, De Gooijer, Cornedine J., van Werkhoven, Erik, van den Heuvel, Michel M., Baas, Paul
Published in Transl Lung Cancer Res (2020)

Recent Advances and Future Perspective of DC-Based Therapy in NSCLC

by van der Hoorn, Iris A. E., Flórez-Grau, Georgina, van den Heuvel, Michel M., de Vries, I. Jolanda M., Piet, Berber
Published in Front Immunol (2021)

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy

by van den Heuvel, Michel M, Verheij, Marcel, Boshuizen, Rogier, Belderbos, José, Dingemans, Anne-Marie C, De Ruysscher, Dirk, Laurent, Julien, Tighe, Robert, Haanen, John, Quaratino, Sonia
Published in J Transl Med (2015)

A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions

by de Rouw, Nikki, Visser, Sabine, Koolen, Stijn L. W., Aerts, Joachim G. J. V., van den Heuvel, Michel M., Derijks, Hieronymus J., Burger, David M., ter Heine, Rob
Published in Cancer Chemother Pharmacol (2019)

Rethinking the Application of Pemetrexed for Patients with Renal Impairment: A Pharmacokinetic Analysis

by de Rouw, Nikki, Boosman, Rene J., Huitema, Alwin D. R., Hilbrands, Luuk B., Svensson, Elin M., Derijks, Hieronymus J., van den Heuvel, Michel M., Burger, David M., ter Heine, Rob
Published in Clin Pharmacokinet (2021)

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation

by Groenendijk, Floris H, Mellema, Wouter W, van der Burg, Eline, Schut, Eva, Hauptmann, Michael, Horlings, Hugo M, Willems, Stefan M, van den Heuvel, Michel M, Jonkers, Jos, Smit, Egbert F, Bernards, René
Published in Int J Cancer (2015)

Clinical Utility of Plasma-Based Comprehensive Molecular Profiling in Advanced Non–Small-Cell Lung Cancer

by Schouten, Robert D., Vessies, Daan C. L., Bosch, Linda J. W., Barlo, Nicole P., van Lindert, Anne S. R., Cillessen, Saskia A. G. M., van den Broek, Daan, van den Heuvel, Michel M., Monkhorst, Kim
Published in JCO Precis Oncol (2021)

Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions

by Hummelink, Karlijn, Muller, Mirte, Linders, Theodora C., van der Noort, Vincent, Nederlof, Petra M., Baas, Paul, Burgers, Sjaak, Smit, Egbert F., Meijer, Gerrit A., van den Heuvel, Michel M., van den Broek, Daan, Monkhorst, Kim
Published in ERJ Open Res (2019)

Risk Assessment After a Severe Hospital-Acquired Infection Associated With Carbapenemase-Producing Pseudomonas aeruginosa

by Hopman, Joost, Meijer, Corianne, Kenters, Nikki, Coolen, Jordy P. M., Ghamati, Mohammad R., Mehtar, Shaheen, van Crevel, Reinout, Morshuis, Wim J., Verhagen, Ad F. T. M., van den Heuvel, Michel M., Voss, Andreas, Wertheim, Heiman F. L.
Published in JAMA Netw Open (2019)

FGFR1, 2 and 3 protein overexpression and molecular aberrations of FGFR3 in early stage non‐small cell lung cancer

by Theelen, Willemijn SME, Mittempergher, Lorenza, Willems, Stefan M, Bosma, Astrid J, Peters, Dennis DGC, van der Noort, Vincent, Japenga, Eva J, Peeters, Ton, Koole, Koos, Šuštić, Tonći, Blaauwgeers, JL, van Noesel, Carel J, Bernards, René, van den Heuvel, Michel M
Published in J Pathol Clin Res (2016)

Selumetinib Plus Docetaxel Compared With Docetaxel Alone and Progression-Free Survival in Patients With KRAS-Mutant Advanced Non–Small Cell Lung Cancer: The SELECT-1 Randomized Cli...

by Jänne, Pasi A., van den Heuvel, Michel M., Barlesi, Fabrice, Cobo, Manuel, Mazieres, Julien, Crinò, Lucio, Orlov, Sergey, Blackhall, Fiona, Wolf, Juergen, Garrido, Pilar, Poltoratskiy, Artem, Mariani, Gabriella, Ghiorghiu, Dana, Kilgour, Elaine, Smith, Paul, Kohlmann, Alexander, Carlile, David J., Lawrence, David, Bowen, Karin, Vansteenkiste, Johan
Published in JAMA (2017)

Predicting survival in malignant pleural effusion: development and validation of the LENT prognostic score

by Clive, Amelia O, Kahan, Brennan C, Hooper, Clare E, Bhatnagar, Rahul, Morley, Anna J, Zahan-Evans, Natalie, Bintcliffe, Oliver J, Boshuizen, Rogier C, Fysh, Edward T H, Tobin, Claire L, Medford, Andrew R L, Harvey, John E, van den Heuvel, Michel M, Lee, Y C Gary, Maskell, Nick A
Published in Thorax (2014)

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in non-small cell lung cancer

by Theelen, Willemijn S. M. E., Kuilman, Thomas, Schulze, Katja, Zou, Wei, Krijgsman, Oscar, Peters, Dennis D. G. C., Cornelissen, Sten, Monkhorst, Kim, Sarma, Pranamee, Sumiyoshi, Teiko, Amler, Lukas C., Willems, Stefan M., Blaauwgeers, Johannes L. G., van Noesel, Carel J. M., Peeper, Daniel S., van den Heuvel, Michel M., Kowanetz, Marcin
Published in PLoS One (2019)

Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

by De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Published in Oncoimmunology (2019)

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity

by van den Broek, Daan, Hiltermann, T. Jeroen N., Biesma, Bonne, Dinjens, Winand N. M., 't Hart, Nils A., Hinrichs, John W. J., Leers, Mathie P. G., Monkhorst, Kim, van Oosterhout, Matthijs, Scharnhorst, Volkher, Schuuring, Ed, Speel, Ernst-Jan M., van den Heuvel, Michel M., van Schaik, Ron H. N., von der Thüsen, Jan, Willems, Stefan M., de Visser, Leonie, Ligtenberg, Marjolijn J. L.
Published in Front Oncol (2020)

Rationale and design of the PRAETORIAN-COVID trial: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrom...

by Gommans, D. H. Frank, Nas, Joris, Pinto-Sietsma, Sara-Joan, Koop, Yvonne, Konst, Regina E., Mensink, Frans, Aarts, Goaris W.A., Konijnenberg, Lara S.F., Cortenbach, Kimberley, Verhaert, Dominique V.M., Thannhauser, Jos, Mol, Jan-Quinten, Rooijakkers, Maxim J.P., Vos, Jacqueline L., van Rumund, Anouke, Vart, Priya, Hassing, Robert-Jan, Cornel, Jan-Hein, de Jager, C. Peter C., van den Heuvel, Michel M., van der Hoeven, Hans G., Verbon, Annelies, Pinto, Yigal M., van Royen, Niels, van Kimmenade, Roland R.J., de Leeuw, Peter W., van Agtmael, Michiel A., Bresser, Paul, van Gilst, Wiek H., Vonk-Noordergraaf, Anton, Tijssen, Jan G.P., van Royen, Niels, de Jager, C. Peter C., van den Heuvel, Michel M., van der Hoeven, Hans G., Verbon, Annelies, Pinto, Yigal M., van Kimmenade, Roland R.J.
Published in Am Heart J (2020)

Implementation of a Multicenter Biobanking Collaboration for Next‐Generation Sequencing‐Based Biomarker Discovery Based on Fresh Frozen Pretreatment Tumor Tissue Biopsies

by Bins, Sander, Cirkel, Geert A., Gadellaa‐Van Hooijdonk, Christa G., Weeber, Fleur, Numan, Isaac J., Bruggink, Annette H., van Diest, Paul J., Willems, Stefan M., Veldhuis, Wouter B., van den Heuvel, Michel M., de Knegt, Rob J., Koudijs, Marco J., van Werkhoven, Erik, Mathijssen, Ron H.J., Cuppen, Edwin, Sleijfer, Stefan, Schellens, Jan H.M., Voest, Emile E., Langenberg, Marlies H.G., de Jonge, Maja J.A., Steeghs, Neeltje, Lolkema, Martijn P.
Published in Oncologist (2016)

Durvalumab With or Without Tremelimumab vs Standard Chemotherapy in First-line Treatment of Metastatic Non–Small Cell Lung Cancer: The MYSTIC Phase 3 Randomized Clinical Trial

by Rizvi, Naiyer A., Cho, Byoung Chul, Reinmuth, Niels, Lee, Ki Hyeong, Luft, Alexander, Ahn, Myung-Ju, van den Heuvel, Michel M., Cobo, Manuel, Vicente, David, Smolin, Alexey, Moiseyenko, Vladimir, Antonia, Scott J., Le Moulec, Sylvestre, Robinet, Gilles, Natale, Ronald, Schneider, Jeffrey, Shepherd, Frances A., Geater, Sarayut Lucien, Garon, Edward B., Kim, Edward S., Goldberg, Sarah B., Nakagawa, Kazuhiko, Raja, Rajiv, Higgs, Brandon W., Boothman, Anne-Marie, Zhao, Luping, Scheuring, Urban, Stockman, Paul K., Chand, Vikram K., Peters, Solange
Published in JAMA Oncol (2020)