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A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions
PURPOSE: Pemetrexed is a widely used cytostatic agent with an established exposure–response relationship. Although dosing is based on body surface area (BSA), large interindividual variability in pemetrexed plasma concentrations is observed. Therapeutic drug monitoring (TDM) can be a feasible strate...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994532/ https://ncbi.nlm.nih.gov/pubmed/31853639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-019-04006-x |
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