6. Dose Adjustments Based on Pharmacogenetics of CYP450 Enzymes

Por van Schaik, Ron H.N.
Publicado no EJIFCC (2008)

The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations

Por Elens, Laure, Hesselink, Dennis A, van Schaik, Ron H N, van Gelder, Teun
Publicado em 2013

A Guide to the Current Web-Based Resources in Pharmacogenomics

Por Glubb, Dylan M., Paugh, Steven W., van Schaik, Ron H.N., Innocenti, Federico
Publicado em 2013

Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks

Por Elens, Laure, Bouamar, Rachida, Shuker, Nauras, Hesselink, Dennis A, van Gelder, Teun, van Schaik, Ron H N
Publicado em 2014

Genetic Variation in the Multidrug and Toxin Extrusion 1 Transporter Protein Influences the Glucose-Lowering Effect of Metformin in Patients With Diabetes: A Preliminary Study

Por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H.N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H.Ch.
Publicado em 2009

OCT1 polymorphism is associated with response and survival time in anti-Parkinsonian drug users

Por Becker, Matthijs L., Visser, Loes E., van Schaik, Ron H. N., Hofman, Albert, Uitterlinden, André G., Stricker, Bruno H. Ch.
Publicado em 2010

Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil

Por Gensburger, Olivier, Van Schaik, Ron H. N., Picard, Nicolas, Le Meur, Yannick, Rousseau, Annick, Woillard, Jean-Baptiste, Van Gelder, Teun, Marquet, Pierre
Publicado em 2010

Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants

Por Bijl, Monique J, Visser, Loes E, Hofman, Albert, Vulto, Arnold G, van Gelder, Teun, Stricker, Bruno H Ch, van Schaik, Ron H N
Publicado em 2008

CYP3A5, ABCB1 and SLCO1B1 Polymorphisms and Pharmacokinetics and Virologic Outcome of Lopinavir/Ritonavir in HIV-infected Children

Por Rakhmanina, Natella Y., Neely, Michael, Van Schaik, Ron H.N., Gordish-Dressman, Heather, Williams, Keetra D., Soldin, Steven J., van den Anker, John N.
Publicado em 2011

Variation in the CYP2D6 gene is associated with a lower serum sodium concentration in patients on antidepressants

Por Kwadijk-de Gijsel, Sonja, Bijl, Monique J, Visser, Loes E, van Schaik, Ron H N, Hofman, Albert, Vulto, Arnold G, van Gelder, Teun, Ch Stricker, Bruno H
Publicado em 2009

The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation

Por de Wildt, Saskia N., van Schaik, Ron H. N., Soldin, Offie P., Soldin, Steve J., Brojeni, Parvaneh Yazdani, van der Heiden, Ilse P., Parshuram, Chris, Nulman, Irena, Koren, Gideon
Publicado em 2011

Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose

Por Andrews, Louise M., de Winter, Brenda C.M., Tang, Jiang-Tao, Shuker, Nauras, Bouamar, Rachida, van Schaik, Ron H.N., Koch, Birgit C.P., van Gelder, Teun, Hesselink, Dennis A.
Publicado no Transplant Direct (2017)

4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes

Por de Graan, Anne-Joy M, Sparreboom, Alex, de Bruijn, Peter, de Jonge, Evert, van der Holt, Bronno, Wiemer, Erik A C, Verweij, Jaap, Mathijssen, Ron H J, van Schaik, Ron H N
Publicado no Br J Clin Pharmacol (2015)

Prostate Health Index (phi) Improves Multivariable Risk Prediction of Aggressive Prostate Cancer

Por Loeb, Stacy, Shin, Sanghyuk S., Broyles, Dennis L., Wei, John T., Sanda, Martin, Klee, George, Partin, Alan W., Sokoll, Lori, Chan, Daniel W., Bangma, Chris H., van Schaik, Ron H. N., Slawin, Kevin M., Marks, Leonard S., Catalona, William J.
Publicado no BJU Int (2016)

The Prostate Health Index Selectively Identifies Clinically Significant Prostate Cancer

Por Loeb, Stacy, Sanda, Martin G., Broyles, Dennis L., Shin, Sanghyuk S., Bangma, Chris H., Wei, John T., Partin, Alan W., Klee, George G., Slawin, Kevin M., Marks, Leonard S., van Schaik, Ron H. N., Chan, Daniel W., Sokoll, Lori J., Cruz, Amabelle B., Mizrahi, Isaac A., Catalona, William J.
Publicado no J Urol (2014)

A Multi-Center Study of [−2]Pro-Prostate-Specific Antigen (PSA) in Combination with PSA and Free PSA for Prostate Cancer Detection in the 2.0 to 10.0 ng/mL PSA Range

Por Catalona, William J., Partin, Alan W., Sanda, Martin G., Wei, John T., Klee, George G., Bangma, Chris H., Slawin, Kevin M., Marks, Leonard S., Loeb, Stacy, Broyles, Dennis L., Shin, Sanghyuk S., Cruz, Amabelle B., Chan, Daniel W., Sokoll, Lori J., Roberts, William L., van Schaik, Ron H.N., Mizrahi, Isaac A.
Publicado em 2011

CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity

Por de Graan, Anne-Joy M., Elens, Laure, Sprowl, Jason A., Sparreboom, Alex, Friberg, Lena E., van der Holt, Bronno, de Raaf, Pleun J., de Bruijn, Peter, Engels, Frederike K., Eskens, Ferry A.L.M., Wiemer, Erik A.C., Verweij, Jaap, Mathijssen, Ron H.J., van Schaik, Ron H.N.
Publicado em 2013

Prospective, Multi-Center Evaluation of the Beckman Coulter Prostate Health Index Using WHO Calibration

Por Loeb, Stacy, Sokoll, Lori J., Broyles, Dennis L., Bangma, Chris H., van Schaik, Ron H.N., Klee, George G., Wei, John T., Sanda, Martin G., Partin, Alan W., Slawin, Kevin M., Marks, Leonard S., Mizrahi, Isaac A., Shin, Sanghyuk S., Cruz, Amabelle B., Chan, Daniel W., Roberts, William L., Catalona, William J.
Publicado no J Urol (2012)

Circadian variation in tamoxifen pharmacokinetics in mice and breast cancer patients

Por Binkhorst, Lisette, Kloth, Jacqueline S. L., de Wit, Annelieke S., de Bruijn, Peter, Lam, Mei H., Chaves, Ines, Burger, Herman, van Alphen, Robbert J., Hamberg, Paul, van Schaik, Ron H. N., Jager, Agnes, Koch, Birgit C. P., Wiemer, Erik A. C., van Gelder, Teun, van der Horst, Gijsbertus T. J., Mathijssen, Ron H. J.
Publicado no Breast Cancer Res Treat (2015)

Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel

Por de Graan, Anne-Joy M., Lancaster, Cynthia S., Obaidat, Amanda, Hagenbuch, Bruno, Elens, Laure, Friberg, Lena E., de Bruijn, Peter, Hu, Shuiying, Gibson, Alice A., Bruun, Gitte H., Corydon, Thomas J., Mikkelsen, Torben S., Walker, Aisha L., Du, Guoqing, Loos, Walter J., van Schaik, Ron H. N., Baker, Sharyn D., Mathijssen, Ron H. J., Sparreboom, Alex
Publicado em 2012