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Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil

BACKGROUND: Type I and II inosine monophosphate dehydrogenases (IMPDH) are the targets of mycophenolic acid (MPA), a widely used immunosuppressant. The aims of this study were: to check the presence of controversial polymorphisms in the IMPDH II gene; to look for new ones; and to investigate potenti...

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Detalhes bibliográficos
Main Authors: Gensburger, Olivier, Van Schaik, Ron H. N., Picard, Nicolas, Le Meur, Yannick, Rousseau, Annick, Woillard, Jean-Baptiste, Van Gelder, Teun, Marquet, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235084/
https://ncbi.nlm.nih.gov/pubmed/20679962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e32833d8cf5
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