Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8*2 variant allele

AIM: In renal transplant patients given mycophenolate mofetil (MMF), we investigated the relationship between the digestive adverse events and polymorphisms in the UGT genes involved in mycophenolic acid (MPA) intestinal metabolism and biliary excretion of its phase II metabolites. METHODS: Clinical...

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Detalhes bibliográficos
Main Authors: Woillard, Jean-Baptiste, Rerolle, Jean-Philippe, Picard, Nicolas, Rousseau, Annick, Drouet, Mireille, Munteanu, Eliza, Essig, Marie, Marquet, Pierre, Le Meur, Yann
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883760/
https://ncbi.nlm.nih.gov/pubmed/20565459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03625.x
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