Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8*2 variant allele

AIM: In renal transplant patients given mycophenolate mofetil (MMF), we investigated the relationship between the digestive adverse events and polymorphisms in the UGT genes involved in mycophenolic acid (MPA) intestinal metabolism and biliary excretion of its phase II metabolites. METHODS: Clinical...

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Bibliografiska uppgifter
Huvudupphovsmän: Woillard, Jean-Baptiste, Rerolle, Jean-Philippe, Picard, Nicolas, Rousseau, Annick, Drouet, Mireille, Munteanu, Eliza, Essig, Marie, Marquet, Pierre, Le Meur, Yann
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2010
Ämnen:
Pharmacogenetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883760/
https://ncbi.nlm.nih.gov/pubmed/20565459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03625.x
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