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Inosine 5’-Monophosphate Dehydrogenase 1 Haplotypes and Association with Mycophenolate Mofetil Gastrointestinal Intolerance in Pediatric Heart Transplant Patients

OBJECTIVE: Mycophenolate mofetil (MMF), the most commonly used adjuvant immunosuppressant in pediatric heart transplantation, has frequent gastrointestinal (GI) adverse events. Single nucleotide polymorphisms (SNPs) in inosine 5’-monophosphate dehydrogenase I (IMPDH1) may contribute to MMF GI intole...

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Bibliografiske detaljer
Main Authors: Ohmann, Erin L, Burckart, Gilbert J., Chen, Yan, Pravica, Vera, Brooks, Maria M., Zeevi, Adriana, Webber, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955782/
https://ncbi.nlm.nih.gov/pubmed/20649757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3046.2010.01367.x
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