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Inosine 5’-Monophosphate Dehydrogenase 1 Haplotypes and Association with Mycophenolate Mofetil Gastrointestinal Intolerance in Pediatric Heart Transplant Patients
OBJECTIVE: Mycophenolate mofetil (MMF), the most commonly used adjuvant immunosuppressant in pediatric heart transplantation, has frequent gastrointestinal (GI) adverse events. Single nucleotide polymorphisms (SNPs) in inosine 5’-monophosphate dehydrogenase I (IMPDH1) may contribute to MMF GI intole...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955782/ https://ncbi.nlm.nih.gov/pubmed/20649757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-3046.2010.01367.x |
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