No Effect of Dose Adjustment to the CYP2D6 Genotype in Patients With Severe Mental Illness

Background: The CYP2D6 enzyme is involved in the metabolism of numerous psychopharmacological drugs. Guidelines recommend how to adjust the dose of medication based on the CYP2D6 genotype. Aims: To evaluate the effect of dose adjustment to the CYP2D6 genotype and phenotype, in patients with severe m...

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Detalhes bibliográficos
Publicado no:Front Psychiatry
Main Authors: Koopmans, Anne B., Vinkers, David J., Poulina, Igmar T., Gelan, Petra J. A., van Schaik, Ron H. N., Hoek, Hans W., van Harten, Peter N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Psychiatry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090167/
https://ncbi.nlm.nih.gov/pubmed/30131727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2018.00349
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