Molecular Pathology of Well-Differentiated Pulmonary and Thymic Neuroendocrine Tumors: What Do Pathologists Need to Know?

por Volante, Marco, Mete, Ozgur, Pelosi, Giuseppe, Roden, Anja C., Speel, Ernst Jan M., Uccella, Silvia
Publicado no Endocr Pathol (2021)

Cell-Free HPV-DNA as a Biomarker for Oropharyngeal Squamous Cell Carcinoma—A Step Towards Personalized Medicine?

por Wuerdemann, Nora, Jain, Rishabh, Adams, Anne, Speel, Ernst-Jan M., Wagner, Steffen, Joosse, Simon A., Klussmann, Jens P.
Publicado no Cancers (Basel) (2020)

Evidence for different molecular parameters in head and neck squamous cell carcinoma of nonsmokers and nondrinkers: Systematic review and meta‐analysis on HPV, p16, and TP53

por Mulder, Frans J., Pierssens, Damiana D. C. G., Baijens, Laura W. J., Kremer, Bernd, Speel, Ernst‐Jan M.
Publicado no Head Neck (2020)

Emerging role of human polyomaviruses 6 and 7 in human cancers

por Klufah, Faisal, Mobaraki, Ghalib, Liu, Dan, Alharbi, Raed A., Kurz, Anna Kordelia, Speel, Ernst Jan M., Winnepenninckx, Véronique, zur Hausen, Axel
Publicado no Infect Agent Cancer (2021)

Integration of HPV6 and Downregulation of AKR1C3 Expression Mark Malignant Transformation in a Patient with Juvenile-Onset Laryngeal Papillomatosis

por Huebbers, Christian Ulrich, Preuss, Simon Florian, Kolligs, Jutta, Vent, Julia, Stenner, Markus, Wieland, Ulrike, Silling, Steffi, Drebber, Uta, Speel, Ernst-Jan M., Klussmann, Jens Peter
Publicado em 2013

Frequent detection of human polyomavirus 6 in keratoacanthomas

por Beckervordersandforth, Jan, Pujari, Sreedhar, Rennspiess, Dorit, Speel, Ernst Jan M., Winnepenninckx, Véronique, Diaz, Carlos, Weyers, Wolfgang, Haugg, Anke Maria, Kurz, Anna Kordelia, zur Hausen, Axel
Publicado no Diagn Pathol (2016)

Genomic Alterations in Well-Differentiated Gastrointestinal and Bronchial Neuroendocrine Tumors (Carcinoids) : Marked Differences Indicating Diversity in Molecular Pathogenesis

por Zhao, Jianming, de Krijger, Roland R., Meier, Dorette, Speel, Ernst-Jan M., Saremaslani, Parvin, Muletta-Feurer, Seraina, Matter, Claudia, Roth, Jürgen, Heitz, Philipp U., Komminoth, Paul
Publicado em 2000

Vismodegib-resistant basal cell carcinomas in basal cell nevus syndrome: Clinical approach and genetic analysis

por Sinx, Kelly A.E., Roemen, Guido M.J.M., van Zutven, Virrie, Janssen, Renske, Speel, Ernst-Jan M., Steijlen, Peter M., van Geel, Michel, Mosterd, Klara
Publicado no JAAD Case Rep (2018)

Identification of CD90 as Putative Cancer Stem Cell Marker and Therapeutic Target in Insulinomas

por Buishand, Floryne O., Arkesteijn, Ger J.A., Feenstra, Laurien R., Oorsprong, Claire W.D., Mestemaker, Margiet, Starke, Achim, Speel, Ernst-Jan M., Kirpensteijn, Jolle, Mol, Jan A.
Publicado no Stem Cells Dev (2016)

Increase in Viral Load, Viral Integration, and Gain of Telomerase Genes during Uterine Cervical Carcinogenesis can be Simultaneously Assessed by the HPV 16/18 MLPA-Assay

por Theelen, Wendy, Speel, Ernst-Jan M., Herfs, Michael, Reijans, Martin, Simons, Guus, Meulemans, Els V., Baldewijns, Marcella M., Ramaekers, Frans C.S., Somja, Joan, Delvenne, Philippe, Hopman, Anton H.N.
Publicado em 2010

High Prevalence of Human Polyomavirus 7 in Cholangiocarcinomas and Adjacent Peritumoral Hepatocytes: Preliminary Findings

por Klufah, Faisal, Mobaraki, Ghalib, Chteinberg, Emil, Alharbi, Raed A., Winnepenninckx, Véronique, Speel, Ernst Jan M., Rennspiess, Dorit, Olde Damink, Steven W., Neumann, Ulf P., Kurz, Anna Kordelia, Samarska, Iryna, zur Hausen, Axel
Publicado no Microorganisms (2020)

Presence of Human Papillomavirus and Epstein–Barr Virus, but Absence of Merkel Cell Polyomavirus, in Head and Neck Cancer of Non-Smokers and Non-Drinkers

por Mulder, Frans J., Klufah, Faisal, Janssen, Famke M. E., Farshadpour, Farzaneh, Willems, Stefan M., de Bree, Remco, zur Hausen, Axel, van den Hout, Mari F. C. M., Kremer, Bernd, Speel, Ernst-Jan M.
Publicado no Front Oncol (2021)

Chemotherapy for pulmonary large cell neuroendocrine carcinomas: does the regimen matter?

por Derks, Jules L., van Suylen, Robert Jan, Thunnissen, Erik, den Bakker, Michael A., Groen, Harry J., Smit, Egbert F., Damhuis, Ronald A., van den Broek, Esther C., Speel, Ernst-Jan M., Dingemans, Anne-Marie C.
Publicado no Eur Respir J (2017)

BRAF(V600E) immunopositive Melanomas Show Low Frequency of Heterogeneity and Association With Epithelioid Tumor Cells: A STROBE-Compliant article

por Verlinden, Ivana, van den Hurk, Karin, Clarijs, Ruud, Willig, Arjan P., Stallinga, Cecile M.H.A., Roemen, Guido M.J.M., van den Oord, Joost J., zur Hausen, Axel, Speel, Ernst-Jan M., Winnepenninckx, Véronique J.L.
Publicado no Medicine (Baltimore) (2014)

Comprehensive Analysis of HPV16 Integration in OSCC Reveals No Significant Impact of Physical Status on Viral Oncogene and Virally Disrupted Human Gene Expression

por Olthof, Nadine C., Speel, Ernst-Jan M., Kolligs, Jutta, Haesevoets, Annick, Henfling, Mieke, Ramaekers, Frans C. S., Preuss, Simon F., Drebber, Uta, Wieland, Ulrike, Silling, Steffi, Lam, Wan L., Vucic, Emily A., Kremer, Bernd, Klussmann, Jens-P., Huebbers, Christian U.
Publicado em 2014

Type I Interferons in the Treatment of Pancreatic Cancer: Mechanisms of Action and Role of Related Receptors

por Vitale, Giovanni, van Eijck, Casper H. J., van Koetsveld Ing, Peter M., Erdmann, Joris I., Speel, Ernst Jan M., van der Wansem Ing, Katy, Mooij, Diana M., Colao, Annamaria, Lombardi, Gaetano, Croze, Ed, Lamberts, Steven W. J., Hofland, Leo J.
Publicado em 2007

Deletions of 11q22.3-q25 Are Associated with Atypical Lung Carcinoids and Poor Clinical Outcome

por Swarts, Dorian R.A., Claessen, Sandra M.H., Jonkers, Yvonne M.H., van Suylen, Robert-Jan, Dingemans, Anne-Marie C., de Herder, Wouter W., de Krijger, Ronald R., Smit, Egbert F., Thunnissen, Frederik B.J.M., Seldenrijk, Cornelis A., Vink, Aryan, Perren, Aurel, Ramaekers, Frans C.S., Speel, Ernst-Jan M.
Publicado em 2011

Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines

por Olthof, Nadine C., Huebbers, Christian U., Kolligs, Jutta, Henfling, Mieke, Ramaekers, Frans C.S., Cornet, Iris, van Lent-Albrechts, Josefa A., Stegmann, Sander P.A., Silling, Steffi, Wieland, Ulrike, Carey, Thomas E., Walline, Heather M., Gollin, Susanne M., Hoffmann, Thomas K., de Winter, Johan, Kremer, Bernd, Klussmann, Jens-Peter, Speel, Ernst-Jan M.
Publicado no Int J Cancer (2014)

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity

por van den Broek, Daan, Hiltermann, T. Jeroen N., Biesma, Bonne, Dinjens, Winand N. M., 't Hart, Nils A., Hinrichs, John W. J., Leers, Mathie P. G., Monkhorst, Kim, van Oosterhout, Matthijs, Scharnhorst, Volkher, Schuuring, Ed, Speel, Ernst-Jan M., van den Heuvel, Michel M., van Schaik, Ron H. N., von der Thüsen, Jan, Willems, Stefan M., de Visser, Leonie, Ligtenberg, Marjolijn J. L.
Publicado no Front Oncol (2020)

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics

por Eijkelenboom, Astrid, Tops, Bastiaan B. J., van den Berg, Anke, van den Brule, Adrianus J. C., Dinjens, Winand N. M., Dubbink, Hendrikus J., ter Elst, Arja, Geurts-Giele, Willemina R. R., Groenen, Patricia J. T. A., Groenendijk, Floris H., Heideman, Daniëlle A. M., Huibers, Manon M. H., Huijsmans, Cornelis J. J., Jeuken, Judith W. M., van Kempen, Léon C., Korpershoek, Esther, Kroeze, Leonie I., de Leng, Wendy W. J., van Noesel, Carel J. M., Speel, Ernst-Jan M., Vogel, Maartje J., van Wezel, Tom, Nederlof, Petra M., Schuuring, Ed, Ligtenberg, Marjolijn J. L.
Publicado no Virchows Arch (2019)