Increase in Viral Load, Viral Integration, and Gain of Telomerase Genes during Uterine Cervical Carcinogenesis can be Simultaneously Assessed by the HPV 16/18 MLPA-Assay

Oncogenic human papillomavirus (HPV) infection is the most important risk factor in cervical carcinogenesis cases; high viral loads, viral integration into the host genome, and gain of the telomerase-related genes, TERT and TERC, are all factors associated with progression to cancer. A recently deve...

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Detalhes bibliográficos
Main Authors: Theelen, Wendy, Speel, Ernst-Jan M., Herfs, Michael, Reijans, Martin, Simons, Guus, Meulemans, Els V., Baldewijns, Marcella M., Ramaekers, Frans C.S., Somja, Joan, Delvenne, Philippe, Hopman, Anton H.N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947296/
https://ncbi.nlm.nih.gov/pubmed/20813962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090901
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