Comprehensive Analysis of HPV16 Integration in OSCC Reveals No Significant Impact of Physical Status on Viral Oncogene and Virally Disrupted Human Gene Expression

Infection with high-risk human papillomavirus (HPV) type 16 is an independent risk factor for the development of oropharyngeal squamous cell carcinomas (OSCC). However, it is unclear whether viral integration is an essential hallmark in the carcinogenic process of OSCC and whether HPV integration co...

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Detalhes bibliográficos
Main Authors: Olthof, Nadine C., Speel, Ernst-Jan M., Kolligs, Jutta, Haesevoets, Annick, Henfling, Mieke, Ramaekers, Frans C. S., Preuss, Simon F., Drebber, Uta, Wieland, Ulrike, Silling, Steffi, Lam, Wan L., Vucic, Emily A., Kremer, Bernd, Klussmann, Jens-P., Huebbers, Christian U.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933331/
https://ncbi.nlm.nih.gov/pubmed/24586376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088718
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