Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines

HPV-related HNSCC generally have a better prognosis than HPV-negative HNSCC. However, a subgroup of HPV-positive tumors with poor prognosis has been recognized, particularly related to smoking, EGFR overexpression and chromosomal instability. Viral integration into the host genome might contribute t...

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Publicado no:Int J Cancer
Main Authors: Olthof, Nadine C., Huebbers, Christian U., Kolligs, Jutta, Henfling, Mieke, Ramaekers, Frans C.S., Cornet, Iris, van Lent-Albrechts, Josefa A., Stegmann, Sander P.A., Silling, Steffi, Wieland, Ulrike, Carey, Thomas E., Walline, Heather M., Gollin, Susanne M., Hoffmann, Thomas K., de Winter, Johan, Kremer, Bernd, Klussmann, Jens-Peter, Speel, Ernst-Jan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5370555/
https://ncbi.nlm.nih.gov/pubmed/25082736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29112
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