Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

Non-small cell lung cancer (NSCLC) is the second most prevalent type of cancer. With the current treatment regimens, the mortality rate remains high. Therefore, better therapeutic approaches are necessary. NSCLCs generally possess many genetic mutations and are well infiltrated by T cells (TIL), mak...

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Bibliografische gegevens
Gepubliceerd in:Oncoimmunology
Hoofdauteurs: De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791436/
https://ncbi.nlm.nih.gov/pubmed/31646094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1648170
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