Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

Non-small cell lung cancer (NSCLC) is the second most prevalent type of cancer. With the current treatment regimens, the mortality rate remains high. Therefore, better therapeutic approaches are necessary. NSCLCs generally possess many genetic mutations and are well infiltrated by T cells (TIL), mak...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791436/
https://ncbi.nlm.nih.gov/pubmed/31646094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1648170
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