Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

Non-small cell lung cancer (NSCLC) is the second most prevalent type of cancer. With the current treatment regimens, the mortality rate remains high. Therefore, better therapeutic approaches are necessary. NSCLCs generally possess many genetic mutations and are well infiltrated by T cells (TIL), mak...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: De Groot, Rosa, Van Loenen, Marleen M., Guislain, Aurélie, Nicolet, Benoît P., Freen-Van Heeren, Julian J., Verhagen, Onno J.H.M., Van Den Heuvel, Michel M., De Jong, Jeroen, Burger, Patrick, Van Der Schoot, C.Ellen, Spaapen, Robbert M., Amsen, Derk, Haanen, John B. A. G., Monkhorst, Kim, Hartemink, Koen J., Wolkers, Monika C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2019
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791436/
https://ncbi.nlm.nih.gov/pubmed/31646094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1648170
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