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Using CRISPR to enhance T cell effector function for therapeutic applications
T cells are critical to fight pathogenic microbes and combat malignantly transformed cells in the fight against cancer. To exert their effector function, T cells produce effector molecules, such as the pro-inflammatory cytokines IFN-γ, TNF-α and IL-2. Tumors possess many inhibitory mechanisms that d...
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| I publikationen: | Cytokine X |
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| Huvudupphovsman: | |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Elsevier
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7885876/ https://ncbi.nlm.nih.gov/pubmed/33604565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytox.2020.100049 |
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