A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

Por Le Quesne, John, Maurya, Manisha, Yancheva, Slaveya G., O’Brien, Mary, Popat, Sanjay, Wotherspoon, Andrew C., de Castro, David Gonzalez, Nicholson, Andrew G.
Publicado em 2014

Comparison of Testing Methods for the Detection of BRAF V600E Mutations in Malignant Melanoma: Pre-Approval Validation Study of the Companion Diagnostic Test for Vemurafenib

Por Lopez-Rios, Fernando, Angulo, Barbara, Gomez, Belen, Mair, Debbie, Martinez, Rebeca, Conde, Esther, Shieh, Felice, Vaks, Jeffrey, Langland, Rachel, Lawrence, H. Jeffrey, de Castro, David Gonzalez
Publicado em 2013

Frequency of mutations and polymorphisms in borderline ovarian tumors of known cancer genes

Por Stemke-Hale, Katherine, Shipman, Kristy, Kitsou-Mylona, Isidora, de Castro, David Gonzalez, Hird, Vicky, Brown, Robert, Flanagan, James, Hani Gabra, H, Mills, Gordon B., Agarwal, R, El-Bahrawy, Mona
Publicado em 2012

Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

Por Lee, Jen Y, Garcia-Murillas, Isaac, Cutts, Rosalind J, De Castro, David Gonzalez, Grove, Lorna, Hurley, Tara, Wang, Fuqiang, Nutting, Christopher, Newbold, Katie, Harrington, Kevin, Turner, Nicholas, Bhide, Shreerang
Publicado no Br J Cancer (2017)

Immunologically silent cancer clone transmission from mother to offspring

Por Isoda, Takeshi, Ford, Anthony M., Tomizawa, Daisuke, van Delft, Frederik W., De Castro, David Gonzalez, Mitsuiki, Norkio, Score, Joannah, Taki, Tomohiko, Morio, Tomohiro, Takagi, Masatoshi, Saji, Hiroh, Greaves, Mel, Mizutani, Shuki
Publicado em 2009

Selective FLT3 inhibition of FLT3-ITD(+) acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Por Moore, Andrew S., Faisal, Amir, de Castro, David Gonzalez, Bavetsias, Vassilios, Sun, Chongbo, Atrash, Butrus, Valenti, Melanie, de Haven Brandon, Alexis, Avery, Sian, Mair, Debbie, Mirabella, Fabio, Swansbury, John, Pearson, Andrew D.J., Workman, Paul, Blagg, Julian, Raynaud, Florence I., Eccles, Suzanne A., Linardopoulos, Spiros
Publicado em 2012

Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial

Por Kapp, Joshua R, Diss, Tim, Spicer, James, Gandy, Michael, Schrijver, Iris, Jennings, Lawrence J, Li, Marilyn M, Tsongalis, Gregory J, de Castro, David Gonzalez, Bridge, Julia A, Wallace, Andrew, Deignan, Joshua L, Hing, Sandra, Butler, Rachel, Verghese, Eldo, Latham, Gary J, Hamoudi, Rifat A
Publicado no J Clin Pathol (2015)

Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients

Por Sclafani, Francesco, Chau, Ian, Cunningham, David, Lampis, Andrea, Hahne, Jens Claus, Ghidini, Michele, Lote, Hazel, Zito, Domenico, Tabernero, Josep, Glimelius, Bengt, Cervantes, Andres, Begum, Ruwaida, De Castro, David Gonzalez, Wilson, Sanna Hulkki, Peckitt, Clare, Eltahir, Zakaria, Wotherspoon, Andrew, Tait, Diana, Brown, Gina, Oates, Jacqueline, Braconi, Chiara, Valeri, Nicola
Publicado no Carcinogenesis (2016)

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer

Por Sclafani, Francesco, Chau, Ian, Cunningham, David, Hahne, Jens C., Vlachogiannis, George, Eltahir, Zakaria, Lampis, Andrea, Braconi, Chiara, Kalaitzaki, Eleftheria, De Castro, David Gonzalez, Wotherspoon, Andrew, Capdevila, Jaume, Glimelius, Bengt, Tarazona, Noelia, Begum, Ruwaida, Lote, Hazel, Hulkki Wilson, Sanna, Mentrasti, Giulia, Brown, Gina, Tait, Diana, Oates, Jacqueline, Valeri, Nicola
Publicado no Sci Rep (2018)

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

Por Izquierdo, Elisa, Yuan, Lina, George, Sally, Hubank, Michael, Jones, Chris, Proszek, Paula, Shipley, Janet, Gatz, Susanne A., Stinson, Caedyn, Moore, Andrew S., Clifford, Steven C., Hicks, Debbie, Lindsey, Janet C., Hill, Rebecca M., Jacques, Thomas S., Chalker, Jane, Thway, Khin, O’Connor, Simon, Marshall, Lynley, Moreno, Lucas, Pearson, Andrew, Chesler, Louis, Walker, Brian A., De Castro, David Gonzalez
Publicado no Oncotarget (2017)

Genomic landscape of platinum resistant and sensitive testicular cancers

Por Loveday, Chey, Litchfield, Kevin, Proszek, Paula Z., Cornish, Alex J., Santo, Flavia, Levy, Max, Macintyre, Geoff, Holryod, Amy, Broderick, Peter, Dudakia, Darshna, Benton, Barbara, Bakir, Maise Al, Hiley, Crispin, Grist, Emily, Swanton, Charles, Huddart, Robert, Powles, Tom, Chowdhury, Simon, Shipley, Janet, O’Connor, Simon, Brenton, James D., Reid, Alison, de Castro, David Gonzalez, Houlston, Richard S., Turnbull, Clare
Publicado no Nat Commun (2020)

An evaluation of the challenges to developing tumor BRCA1 and BRCA2 testing methodologies for clinical practice

Por Ellison, Gillian, Ahdesmäki, Miika, Luke, Sally, Waring, Paul M., Wallace, Andrew, Wright, Ronnie, Röthlisberger, Benno, Ludin, Katja, Merkelbach‐Bruse, Sabine, Heydt, Carina, Ligtenberg, Marjolijn J.L., Mensenkamp, Arjen R., de Castro, David Gonzalez, Jones, Thomas, Vivancos, Ana, Kondrashova, Olga, Pauwels, Patrick, Weyn, Christine, Hahnen, Eric, Hauke, Jan, Soong, Richie, Lai, Zhongwu, Dougherty, Brian, Carr, T. Hedley, Johnson, Justin, Mills, John, Barrett, J. Carl
Publicado no Hum Mutat (2017)

Genetics and Prognostication in Splenic Marginal Zone Lymphoma: Revelations from Deep Sequencing

Por Parry, Marina, Rose-Zerilli, Matthew JJ, Ljungström, Viktor, Gibson, Jane, Wang, Jun, Walewska, Renata, Parker, Helen, Parker, Anton, Davis, Zadie, Gardiner, Anne, McIver-Brown, Neil, Kalpadakis, Christina, Xochelli, Aliki, Anagnostopoulos, Achilles, Fazi, Claudia, de Castro, David Gonzalez, Dearden, Claire, Pratt, Guy, Rosenquist, Richard, Ashton-Key, Margaret, Forconi, Francesco, Collins, Andrew, Ghia, Paolo, Matutes, Estella, Pangalis, Gerassimos, Stamatopoulos, Kostas, Oscier, David, Strefford, Jonathan C
Publicado no Clin Cancer Res (2015)

EAPH-05. MOLECULAR PROFILING AND IDENTIFICATION OF TARGETED THERAPIES FOR CHILDREN AND YOUNG ADULTS WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMOURS IN THE UNITED KINGDOM

Por Wasti, Ajla, Carceller, Fernando, George, Sally, Koutroumanidou, Eleni, Izquierdo, Elisa, Guerra, Pilar, Zarowiecki, Magdalena, Campbell, James, Al-Lazikani, Bissan, Marshall, Lynley, Jones, Chris, Clarke, Matthew, Powell, Karen, Crowe, Tracey, Rogers, Tony, Chisholm, Julia, Vaidya, Sucheta, Mandeville, Henry, Saran, Frank, Zebian, Bassel, Hettige, Samantha, Al-Sarraj, Safa, Bridges, Leslie, Jacques, Tom, Hargrave, Darren, Pearson, Andy, Walker, Brian, de Castro, David Gonzalez, Hubank, Michael, Chesler, Louis
Publicado no Neuro Oncol (2018)