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A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

INTRODUCTION: Detection of the ALK rearrangement in a solid tumor gives these patients the option of crizotinib as an oral form of anticancer treatment. The current test of choice is fluorescence in situ hybridization (FISH), but various cheaper and more convenient immunohistochemical (IHC) assays h...

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Détails bibliographiques
Auteurs principaux: Le Quesne, John, Maurya, Manisha, Yancheva, Slaveya G., O’Brien, Mary, Popat, Sanjay, Wotherspoon, Andrew C., de Castro, David Gonzalez, Nicholson, Andrew G.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132045/
https://ncbi.nlm.nih.gov/pubmed/24787965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000157
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