A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material

INTRODUCTION: Detection of the ALK rearrangement in a solid tumor gives these patients the option of crizotinib as an oral form of anticancer treatment. The current test of choice is fluorescence in situ hybridization (FISH), but various cheaper and more convenient immunohistochemical (IHC) assays h...

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Detalhes bibliográficos
Main Authors: Le Quesne, John, Maurya, Manisha, Yancheva, Slaveya G., O’Brien, Mary, Popat, Sanjay, Wotherspoon, Andrew C., de Castro, David Gonzalez, Nicholson, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132045/
https://ncbi.nlm.nih.gov/pubmed/24787965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000157
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