KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer

There are limited data on circulating, cell-free, tumour (ct)DNA analysis in locally advanced rectal cancer (LARC). Digital droplet (dd)PCR was used to investigate KRAS/BRAF mutations in ctDNA from baseline blood samples of 97 LARC patients who were treated with CAPOX followed by chemoradiotherapy,...

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Publicado no:Sci Rep
Main Authors: Sclafani, Francesco, Chau, Ian, Cunningham, David, Hahne, Jens C., Vlachogiannis, George, Eltahir, Zakaria, Lampis, Andrea, Braconi, Chiara, Kalaitzaki, Eleftheria, De Castro, David Gonzalez, Wotherspoon, Andrew, Capdevila, Jaume, Glimelius, Bengt, Tarazona, Noelia, Begum, Ruwaida, Lote, Hazel, Hulkki Wilson, Sanna, Mentrasti, Giulia, Brown, Gina, Tait, Diana, Oates, Jacqueline, Valeri, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780472/
https://ncbi.nlm.nih.gov/pubmed/29362371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19212-5
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