Prior epigenetic priming of cytokine genes in naive T cells is required for their subsequent activation by inducible enhancers

Por James, Sally R, Bevington, Sarah L, Mirabella, Fabio, Boissinot, Marjorie, Baxter, Euan W, Bowers, Sarion R, Cockerill, Peter N
Publicado em 2013

A Conserved Insulator That Recruits CTCF and Cohesin Exists between the Closely Related but Divergently Regulated Interleukin-3 and Granulocyte-Macrophage Colony-Stimulating Factor...

Por Bowers, Sarion R., Mirabella, Fabio, Calero-Nieto, Fernando J., Valeaux, Stephanie, Hadjur, Suzana, Baxter, Euan W., Merkenschlager, Matthias, Cockerill, Peter N.
Publicado em 2009

Hsp70 inhibition induces myeloma cell death via the intracellular accumulation of immunoglobulin and the generation of proteotoxic stress()

Por Zhang, Lei, Fok, Jacqueline J.L., Mirabella, Fabio, Aronson, Lauren I., Fryer, Rosemary A., Workman, Paul, Morgan, Gareth J., Davies, Faith E.
Publicado em 2013

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma

Por Kaiser, Martin F., Johnson, David C., Wu, Ping, Walker, Brian A., Brioli, Annamaria, Mirabella, Fabio, Wardell, Christopher P., Melchor, Lorenzo, Davies, Faith E., Morgan, Gareth J.
Publicado em 2013

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression

Por Li, Ni, Johnson, David C., Weinhold, Niels, Studd, James B., Orlando, Giulia, Mirabella, Fabio, Mitchell, Jonathan S., Meissner, Tobias, Kaiser, Martin, Goldschmidt, Hartmut, Hemminki, Kari, Morgan, Gareth J., Houlston, Richard S.
Publicado no Nat Commun (2016)

A Novel Functional Role for MMSET in RNA Processing Based on the Link Between the REIIBP Isoform and Its Interaction with the SMN Complex

Por Mirabella, Fabio, Murison, Alexander, Aronson, Lauren I., Wardell, Christopher P., Thompson, Andrew J., Hanrahan, Sarah J., Fok, Jacqueline H. L., Pawlyn, Charlotte, Kaiser, Martin F., Walker, Brian A., Davies, Faith E., Morgan, Gareth J.
Publicado em 2014

The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers

Por Baxter, Euan W., Mirabella, Fabio, Bowers, Sarion R., James, Sally R., Bonavita, Aude-Marine, Bertrand, Elisabeth, Strogantsev, Ruslan, Hawwari, Abbas, Bert, Andrew G., de Arce, Andrea Gonzalez, West, Adam G., Bonifer, Constanze, Cockerill, Peter N.
Publicado em 2012

Selective FLT3 inhibition of FLT3-ITD(+) acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Por Moore, Andrew S., Faisal, Amir, de Castro, David Gonzalez, Bavetsias, Vassilios, Sun, Chongbo, Atrash, Butrus, Valenti, Melanie, de Haven Brandon, Alexis, Avery, Sian, Mair, Debbie, Mirabella, Fabio, Swansbury, John, Pearson, Andrew D.J., Workman, Paul, Blagg, Julian, Raynaud, Florence I., Eccles, Suzanne A., Linardopoulos, Spiros
Publicado em 2012

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Por Walker, Brian A, Wardell, Christopher P, Melchor, Lorenzo, Brioli, Annamaria, Johnson, David C, Kaiser, Martin F, Mirabella, Fabio, Lopez-Corral, Lucia, Humphray, Sean, Murray, Lisa, Ross, Mark, Bentley, David, Gutiérrez, Norma C., Garcia-Sanz, Ramón, San Miguel, Jesus, Davies, Faith E, Gonzalez, David, Morgan, Gareth J
Publicado em 2013