The inducible tissue-specific expression of the human IL-3/GM-CSF locus is controlled by a complex array of developmentally regulated enhancers

The closely linked human IL-3 and GM-CSF genes are tightly regulated and are expressed in activated T cells and mast cells. Here we used transgenic mice to study the developmental regulation of this locus and to identify DNA elements required for its correct activity in vivo. Because these two genes...

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Библиографические подробности
Главные авторы: Baxter, Euan W., Mirabella, Fabio, Bowers, Sarion R., James, Sally R., Bonavita, Aude-Marine, Bertrand, Elisabeth, Strogantsev, Ruslan, Hawwari, Abbas, Bert, Andrew G., de Arce, Andrea Gonzalez, West, Adam G., Bonifer, Constanze, Cockerill, Peter N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480713/
https://ncbi.nlm.nih.gov/pubmed/23024272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201915
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