Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

BACKGROUND: Following chemo-radiotherapy (CCRT) for human papilloma virus positive (HPV+) locally advanced head and neck cancer, patients frequently undergo unnecessary neck dissection (ND) and/or repeated biopsies for abnormal PET-CT, which causes significant morbidity. We assessed the role of circ...

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Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Lee, Jen Y, Garcia-Murillas, Isaac, Cutts, Rosalind J, De Castro, David Gonzalez, Grove, Lorna, Hurley, Tara, Wang, Fuqiang, Nutting, Christopher, Newbold, Katie, Harrington, Kevin, Turner, Nicholas, Bhide, Shreerang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Genetics & Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589999/
https://ncbi.nlm.nih.gov/pubmed/28809864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.258
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