Predicting response to radical (chemo)radiotherapy with circulating HPV DNA in locally advanced head and neck squamous carcinoma

BACKGROUND: Following chemo-radiotherapy (CCRT) for human papilloma virus positive (HPV+) locally advanced head and neck cancer, patients frequently undergo unnecessary neck dissection (ND) and/or repeated biopsies for abnormal PET-CT, which causes significant morbidity. We assessed the role of circ...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Lee, Jen Y, Garcia-Murillas, Isaac, Cutts, Rosalind J, De Castro, David Gonzalez, Grove, Lorna, Hurley, Tara, Wang, Fuqiang, Nutting, Christopher, Newbold, Katie, Harrington, Kevin, Turner, Nicholas, Bhide, Shreerang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589999/
https://ncbi.nlm.nih.gov/pubmed/28809864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.258
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