Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: Potential prospects for combined targeted therapeutics

Por ZIMONJIC, DRAZEN B., POPESCU, NICHOLAS C.
Publicado em 2012

DLC1 interaction with S100A10 mediates inhibition of in vitro cell invasion and tumorigenicity of lung cancer cells through a RhoGAP-independent mechanism

Por Yang, Xuyu, Popescu, Nicholas C., Zimonjic, Drazen B.
Publicado em 2011

DLC1 Interaction with α-Catenin Stabilizes Adherens Junctions and Enhances DLC1 Antioncogenic Activity

Por Tripathi, Veenu, Popescu, Nicholas C., Zimonjic, Drazen B.
Publicado em 2012

DLC1 suppresses NF-κB activity in prostate cancer cells due to its stabilizing effect on adherens junctions

Por Tripathi, Veenu, Popescu, Nicholas C, Zimonjic, Drazen B
Publicado em 2014

Effect of KEPI (Ppp1r14c) deletion on morphine analgesia and tolerance in mice of different genetic backgrounds: when a knockout is near a relevant QTL

Por Drgonova, Jana, Zimonjic, Drazen B., Hall, F. Scott, Uhl, George R.
Publicado em 2009

Thirteen-exon-motif signature for vertebrate nuclear and mitochondrial type IB topoisomerases

Por Zhang, Hongliang, Meng, Ling-Hua, Zimonjic, Drazen B., Popescu, Nicholas C., Pommier, Yves
Publicado em 2004

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

Por Zimonjic, Drazen B., Pollock, Jessica L., Westervelt, Peter, Popescu, Nicholas C., Ley, Timothy J.
Publicado em 2000

Amplification and Overexpression of the EMS 1 Oncogene, a Possible Prognostic Marker, in Human Hepatocellular Carcinoma

Por Yuan, Bao-Zhu, Zhou, Xiaoling, Zimonjic, Drazen B., Durkin, Marian E., Popescu, Nicholas C.
Publicado em 2003

Recurrent and Non-Random DNA Copy Number and Chromosome Alterations in c-Myc Transgenic Mouse Model for Hepatocellular Carcinogenesis: Implications for Human Disease

Por Zimonjic, Drazen B., Ullmannova-Benson, Veronika, Factor, Valentina M., Thorgeirsson, Snorri S., Popescu, Nicholas C.
Publicado em 2009

Human mitochondrial topoisomerase I

Por Zhang, Hongliang, Barceló, Juana M., Lee, Benson, Kohlhagen, Glenda, Zimonjic, Drazen B., Popescu, Nicholas C., Pommier, Yves
Publicado em 2001

claudin-18, a Novel Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor, Encodes Lung- and Stomach-Specific Isoforms through Alternative Splicing

Por Niimi, Tomoaki, Nagashima, Kunio, Ward, Jerrold M., Minoo, Parviz, Zimonjic, Drazen B., Popescu, Nicholas C., Kimura, Shioko
Publicado em 2001

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer

Por Bera, Tapan K., Zimonjic, Drazen B., Popescu, Nicholas C., Sathyanarayana, Bangalore K., Kumar, Vasantha, Lee, Byungkook, Pastan, Ira
Publicado em 2002

SMAD5 Gene Expression, Rearrangements, Copy Number, and Amplification at Fragile Site FRA5C in Human Hepatocellular Carcinoma

Por Zimonjic, Drazen B, Durkin, Marian E, Keck-Waggoner, Catherine L, Park, Sang-Won, Thorgeirsson, Snorri S, Popescu, Nicholas C
Publicado em 2003

DLC1 tumor suppressor gene inhibits migration and invasion of multiple myeloma cells through RhoA GTPase pathway

Por Ullmannova-Benson, Veronika, Guan, Ming, Zhou, Xiaoling, Tripathi, Veenu, Yang, Xu-Yu, Zimonjic, Drazen B., Popescu, Nicholas C
Publicado em 2008

Role of SV40 Integration Site at Chromosomal Interval 1q21.1 in Immortalized CRL2504 Cells

Por Liu, Jinglan, Kaur, Gurpreet, Zhawar, Vikramjit K., Zimonjic, Drazen B., Popescu, Nicholas C., Kandpal, Raj P., Athwal, Raghbir S.
Publicado em 2009

Acquired genetic and functional alterations associated with transforming growth factor β type I resistance in Hep3B human hepatocellular carcinoma cell line

Por Zimonjic, Drazen B, Zhou, Xiaoling, Lee, Ju-Seog, Ullmannova-Benson, Veronika, Tripathi, Veenu, Thorgeirsson, Snorri S, Popescu, Nicholas C
Publicado no J Cell Mol Med (2009)

Nab1, a Corepressor of NGFI-A (Egr-1), Contains an Active Transcriptional Repression Domain

Por Swirnoff, Alexander H., Apel, Elizabeth D., Svaren, John, Sevetson, Bradley R., Zimonjic, Drazen B., Popescu, Nicholas C., Milbrandt, Jeffrey
Publicado em 1998

Nonrandom Cytogenetic Alterations in Hepatocellular Carcinoma from Transgenic Mice Overexpressing c-Myc and Transforming Growth Factor-α in the Liver

Por Sargent, Linda M., Zhou, Xuan, Keck, Catherine L., Sanderson, Nancy D., Zimonjic, Drazen B., Popescu, Nicholas C., Thorgeirsson, Snorri S.
Publicado em 1999

DLC-1:a Rho GTPase-activating protein and tumour suppressor

Por Durkin, Marian E, Yuan, Bao-Zhu, Zhou, Xiaoling, Zimonjic, Drazen B, Lowy, Douglas R, Thorgeirsson, Snorri S, Popescu, Nicholas C
Publicado no J Cell Mol Med (2007)

In vitro and in vivo effects of geranylgeranyltransferase I inhibitor P61A6 on non-small cell lung cancer cells

Por Zimonjic, Drazen B, Chan, Lai N, Tripathi, Veenu, Lu, Jie, Kwon, Ohyun, Popescu, Nicholas C, Lowy, Douglas R, Tamanoi, Fuyuhiko
Publicado em 2013