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Nonrandom Cytogenetic Alterations in Hepatocellular Carcinoma from Transgenic Mice Overexpressing c-Myc and Transforming Growth Factor-α in the Liver

Identification of specific and primary chromosomal alterations during the course of neoplastic development is an essential part of defining the genetic basis of cancer. We have developed a transgenic mouse model for liver neoplasia in which chromosomal lesions associated with both the initial stages...

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Detalhes bibliográficos
Main Authors: Sargent, Linda M., Zhou, Xuan, Keck, Catherine L., Sanderson, Nancy D., Zimonjic, Drazen B., Popescu, Nicholas C., Thorgeirsson, Snorri S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866542/
https://ncbi.nlm.nih.gov/pubmed/10233843
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