SMAD5 Gene Expression, Rearrangements, Copy Number, and Amplification at Fragile Site FRA5C in Human Hepatocellular Carcinoma

Signaling by the transforming growth factor (TGF)-family members is transduced from the cell surface to the nucleus by the Smad group of intracellular proteins. Because we detected alterations on the long arm of chromosome 5, we examined the status of the SMAD5 gene in human hepatocellular carcinoma...

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Detalhes bibliográficos
Main Authors: Zimonjic, Drazen B, Durkin, Marian E, Keck-Waggoner, Catherine L, Park, Sang-Won, Thorgeirsson, Snorri S, Popescu, Nicholas C
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502609/
https://ncbi.nlm.nih.gov/pubmed/14670176
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