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Recurrent and Non-Random DNA Copy Number and Chromosome Alterations in c-Myc Transgenic Mouse Model for Hepatocellular Carcinogenesis: Implications for Human Disease

Mouse models for hepatocellular carcinoma (HCC) provide an experimental ground to dissect the genetic and biological complexities of human liver cancer and enhance our ability to gain insights into the relevance of candidate cancer genes. We examined, using spectral karyotyping (SKY) and array-based...

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Detalhes bibliográficos
Main Authors: Zimonjic, Drazen B., Ullmannova-Benson, Veronika, Factor, Valentina M., Thorgeirsson, Snorri S., Popescu, Nicholas C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693875/
https://ncbi.nlm.nih.gov/pubmed/19389504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2008.12.014
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