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Recurrent and Non-Random DNA Copy Number and Chromosome Alterations in c-Myc Transgenic Mouse Model for Hepatocellular Carcinogenesis: Implications for Human Disease

Mouse models for hepatocellular carcinoma (HCC) provide an experimental ground to dissect the genetic and biological complexities of human liver cancer and enhance our ability to gain insights into the relevance of candidate cancer genes. We examined, using spectral karyotyping (SKY) and array-based...

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Detalles Bibliográficos
Autores principales: Zimonjic, Drazen B., Ullmannova-Benson, Veronika, Factor, Valentina M., Thorgeirsson, Snorri S., Popescu, Nicholas C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693875/
https://ncbi.nlm.nih.gov/pubmed/19389504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2008.12.014
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