Nalaganje...

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

We previously generated a transgenic mouse model for acute promyelocytic leukemia (APL) by expressing the promyelocytic leukemia (PML)–retinoic acid receptor (RARα) cDNA in early myeloid cells. This fusion protein causes a myeloproliferative disease in 100% of animals, but only 15–20% of the animals...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Zimonjic, Drazen B., Pollock, Jessica L., Westervelt, Peter, Popescu, Nicholas C., Ley, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC27220/
https://ncbi.nlm.nih.gov/pubmed/11087871
Oznake: Označite
Brez oznak, prvi označite!