Nalaganje...
Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice
We previously generated a transgenic mouse model for acute promyelocytic leukemia (APL) by expressing the promyelocytic leukemia (PML)–retinoic acid receptor (RARα) cDNA in early myeloid cells. This fusion protein causes a myeloproliferative disease in 100% of animals, but only 15–20% of the animals...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The National Academy of Sciences
2000
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC27220/ https://ncbi.nlm.nih.gov/pubmed/11087871 |
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