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DLC1 Interaction with α-Catenin Stabilizes Adherens Junctions and Enhances DLC1 Antioncogenic Activity

The DLC1 (for deleted in liver cancer 1) tumor suppressor gene encodes a RhoGAP protein that inactivates Rho GTPases, which are implicated in regulation of the cytoskeleton and adherens junctions (AJs), a cell-cell adhesion protein complex associated with the actin cytoskeleton. Malignant transforma...

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Autors principals: Tripathi, Veenu, Popescu, Nicholas C., Zimonjic, Drazen B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372231/
https://ncbi.nlm.nih.gov/pubmed/22473989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06580-11
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