Novel functions of PXR in cardiometabolic disease

af Zhou, Changcheng
Udgivet i Biochim Biophys Acta (2016)

Epigenetic impact of endocrine disrupting chemicals on lipid homeostasis and atherosclerosis: a pregnane X receptor-centric view

af Helsley, Robert N, Zhou, Changcheng
Udgivet i Environ Epigenet (2017)

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism

af Zhou, Changcheng, Verma, Suman, Blumberg, Bruce
Udgivet 2009

Deficiency of PXR decreases atherosclerosis in apoE-deficient mice

af Sui, Yipeng, Xu, Jinxian, Rios-Pilier, Jennifer, Zhou, Changcheng
Udgivet 2011

Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice

af Sui, Yipeng, Park, Se-Hyung, Wang, Fang, Zhou, Changcheng
Udgivet i Endocrinology (2018)

Activation of PXR induces hypercholesterolemia in wild-type and accelerates atherosclerosis in apoE deficient mice

af Zhou, Changcheng, King, Nakesha, Chen, Kwan Y., Breslow, Jan L.
Udgivet 2009

Hyperglycemic Ins2(Akita)Ldlr(−/−) mice show severely elevated lipid levels and increased atherosclerosis: a model of type 1 diabetic macrovascular disease

af Zhou, Changcheng, Pridgen, Brian, King, Nakesha, Xu, Jinxian, Breslow, Jan L.
Udgivet 2011

Deficiency of Adipocyte IKKβ Affects Atherosclerotic Plaque Vulnerability in Obese LDLR Deficient Mice

af Lu, Weiwei, Park, Se‐Hyung, Meng, Zhaojie, Wang, Fang, Zhou, Changcheng
Udgivet i J Am Heart Assoc (2019)

Interaction of thrombospondin1 and CD36 contributes to obesity-associated podocytopathy

af Cui, Wenpeng, Maimaitiyiming, Hasiyeti, Zhou, Qi, Norman, Heather, Zhou, Changcheng, Wang, Shuxia
Udgivet i Biochim Biophys Acta (2015)

The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling

af Meng, Zhaojie, Gwag, Taesik, Sui, Yipeng, Park, Se-Hyung, Zhou, Xiangping, Zhou, Changcheng
Udgivet i JCI Insight (2019)

Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR).

af Tabb, Michelle M, Kholodovych, Vladyslav, Grün, Felix, Zhou, Changcheng, Welsh, William J, Blumberg, Bruce
Udgivet 2004

Intestinal Pregnane X Receptor Links Xenobiotic Exposure and Hypercholesterolemia

af Sui, Yipeng, Helsley, Robert N., Park, Se-Hyung, Song, Xiulong, Liu, Zun, Zhou, Changcheng
Udgivet i Mol Endocrinol (2015)

Myeloid-specific deletion of thrombospondin 1 protects against inflammation and insulin resistance in long-term diet-induced obese male mice

af Memetimin, Hasiyet, Li, Dong, Tan, Kaiyuan, Zhou, Changcheng, Liang, Ying, Wu, Yadi, Wang, Shuxia
Udgivet i Am J Physiol Endocrinol Metab (2018)

Pregnane X Receptor Mediates Dyslipidemia Induced by the HIV Protease Inhibitor Amprenavir in Mice

af Helsley, Robert N., Sui, Yipeng, Ai, Ni, Park, Se-Hyung, Welsh, William J., Zhou, Changcheng
Udgivet 2013

Effects of shRNA-mediated silencing of PDE5A3 on intracellular cGMP and free Ca(2+) levels and human prostate smooth muscle cell proliferation from benign prostatic hyperplasia

af Xu, Zheng, Ge, Yuzheng, Jiang, Ke, Xu, Luwei, Zhu, Jiageng, Zhou, Changcheng, Zhou, Liuhua, Jia, Ruipeng
Udgivet i Exp Ther Med (2021)

Bisphenol A and Its Analogues Activate Human Pregnane X Receptor

af Sui, Yipeng, Ai, Ni, Park, Se-Hyung, Rios-Pilier, Jennifer, Perkins, Jordan T., Welsh, William J., Zhou, Changcheng
Udgivet 2012

IKKβ links vascular inflammation to obesity and atherosclerosis

af Sui, Yipeng, Park, Se-Hyung, Xu, Jinxian, Monette, Sébastien, Helsley, Robert N., Han, Seong-Su, Zhou, Changcheng
Udgivet 2014

Myeloid β-Catenin Deficiency Exacerbates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice

af Wang, Fang, Liu, Zun, Park, Se-Hyung, Gwag, Taesik, Lu, Weiwei, Ma, Murong, Sui, Yipeng, Zhou, Changcheng
Udgivet i Arterioscler Thromb Vasc Biol (2018)

Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice

af Sui, Yipeng, Meng, Zhaojie, Park, Se-Hyung, Lu, Weiwei, Livelo, Christopher, Chen, Qi, Zhou, Tong, Zhou, Changcheng
Udgivet i J Lipid Res (2020)

Association of COVID-19 transmission with high levels of ambient pollutants: Initiation and impact of the inflammatory response on cardiopulmonary disease

af Lai, Angela, Chang, Megan L., O'Donnell, Ryan P., Zhou, Changcheng, Sumner, Jennifer A., Hsiai, Tzung K.
Udgivet i Sci Total Environ (2021)