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Pregnane X Receptor Mediates Dyslipidemia Induced by the HIV Protease Inhibitor Amprenavir in Mice

Human immunodeficiency virus (HIV) protease inhibitors (PIs) have been used successfully in extending the life span of people infected with HIV. The use of PIs has also been associated with dyslipidemia and an increased risk of cardiovascular disease, but the underlying mechanisms remain elusive. Se...

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Autori principali: Helsley, Robert N., Sui, Yipeng, Ai, Ni, Park, Se-Hyung, Welsh, William J., Zhou, Changcheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Pharmacology and Experimental Therapeutics 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657097/
https://ncbi.nlm.nih.gov/pubmed/23519392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.113.085753
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