Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice

The pregnane X receptor (PXR) is a nuclear receptor that can be activated by numerous drugs and xenobiotic chemicals. PXR thereby functions as a xenobiotic sensor to coordinately regulate host responses to xenobiotics by transcriptionally regulating many genes involved in xenobiotic metabolism. We h...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Sui, Yipeng, Meng, Zhaojie, Park, Se-Hyung, Lu, Weiwei, Livelo, Christopher, Chen, Qi, Zhou, Tong, Zhou, Changcheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193955/
https://ncbi.nlm.nih.gov/pubmed/32170024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000122
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