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Deficiency of PXR decreases atherosclerosis in apoE-deficient mice
The pregnane X receptor (PXR, also known as SXR) is a nuclear hormone receptor activated by xenobiotics as well as diverse sterols and their metabolites. PXR functions as a xenobiotic sensor to coordinately regulate xenobiotic metabolism via transcriptional regulation of xenobiotic-detoxifying enzym...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151685/ https://ncbi.nlm.nih.gov/pubmed/21685500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M017376 |
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