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Deficiency of PXR decreases atherosclerosis in apoE-deficient mice

The pregnane X receptor (PXR, also known as SXR) is a nuclear hormone receptor activated by xenobiotics as well as diverse sterols and their metabolites. PXR functions as a xenobiotic sensor to coordinately regulate xenobiotic metabolism via transcriptional regulation of xenobiotic-detoxifying enzym...

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Détails bibliographiques
Auteurs principaux: Sui, Yipeng, Xu, Jinxian, Rios-Pilier, Jennifer, Zhou, Changcheng
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151685/
https://ncbi.nlm.nih.gov/pubmed/21685500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M017376
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