Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient

Por Yanagida, Keisuke, Hla, Timothy
Publicado no Annu Rev Physiol (2016)

A dark side to omega-3 fatty acids

Por Yanagida, Keisuke, Hla, Timothy
Publicado no Nature (2017)

Lysophosphatidylcholine Acyltransferase 3 Is the Key Enzyme for Incorporating Arachidonic Acid into Glycerophospholipids during Adipocyte Differentiation

Por Eto, Miki, Shindou, Hideo, Koeberle, Andreas, Harayama, Takeshi, Yanagida, Keisuke, Shimizu, Takao
Publicado em 2012

Lysophosphatidic acid receptor, LPA(6), regulates endothelial blood-brain barrier function: Implication of hepatic encephalopathy

Por Masago, Kayo, Kihara, Yasuyuki, Yanagida, Keisuke, Hamano, Fumie, Nakagawa, Shinsuke, Niwa, Masami, Shimizu, Takao
Publicado no Biochem Biophys Res Commun (2018)

Bioluminescence imaging of G protein-coupled receptor activation in living mice

Por Kono, Mari, Conlon, Elizabeth G., Lux, Samantha Y., Yanagida, Keisuke, Hla, Timothy, Proia, Richard L.
Publicado no Nat Commun (2017)

Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA(6)

Por Yanagida, Keisuke, Masago, Kayo, Nakanishi, Hiroki, Kihara, Yasuyuki, Hamano, Fumie, Tajima, Yoko, Taguchi, Ryo, Shimizu, Takao, Ishii, Satoshi
Publicado em 2009

Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

Por Hishikawa, Daisuke, Yanagida, Keisuke, Nagata, Katsuyuki, Kanatani, Ayumi, Iizuka, Yoshiko, Hamano, Fumie, Yasuda, Megumi, Okamura, Tadashi, Shindou, Hideo, Shimizu, Takao
Publicado no iScience (2020)

The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor

Por Ihara, Yuichiro, Kihara, Yasuyuki, Hamano, Fumie, Yanagida, Keisuke, Morishita, Yasuyuki, Kunita, Akiko, Yamori, Takao, Fukayama, Masashi, Aburatani, Hiroyuki, Shimizu, Takao, Ishii, Satoshi
Publicado em 2010

Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate receptor 1

Por Yanagida, Keisuke, Liu, Catherine H., Faraco, Giuseppe, Galvani, Sylvain, Smith, Helen K., Burg, Nathalie, Anrather, Josef, Sanchez, Teresa, Iadecola, Costantino, Hla, Timothy
Publicado no Proc Natl Acad Sci U S A (2017)

Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

Por Komachi, Mayumi, Sato, Koichi, Tobo, Masayuki, Mogi, Chihiro, Yamada, Takayuki, Ohta, Hideo, Tomura, Hideaki, Kimura, Takao, Im, Dong‐Soon, Yanagida, Keisuke, Ishii, Satoshi, Takeyoshi, Izumi, Okajima, Fumikazu
Publicado no Cancer Sci (2012)

Sphingosine 1-phosphate receptor signaling establishes AP-1 gradients to allow for retinal endothelial cell specialization

Por Yanagida, Keisuke, Engelbrecht, Eric, Niaudet, Colin, Jung, Bongnam, Gaengel, Konstantin, Holton, Kristina, Swendeman, Steven, Liu, Catherine H., Levesque, Michel V., Kuo, Andrew, Fu, Zhongjie, Smith, Lois E. H., Betsholtz, Christer, Hla, Timothy
Publicado no Dev Cell (2020)

The Gα12/13-coupled receptor LPA4 limits proper adipose tissue expansion and remodeling in diet-induced obesity

Por Yanagida, Keisuke, Igarashi, Hidemitsu, Yasuda, Daisuke, Kobayashi, Daiki, Ohto-Nakanishi, Takayo, Akahoshi, Noriyuki, Sekiba, Atsushi, Toyoda, Tsudoi, Ishijima, Tomoko, Nakai, Yuji, Shojima, Nobuhiro, Kubota, Naoto, Abe, Keiko, Kadowaki, Takashi, Ishii, Satoshi, Shimizu, Takao
Publicado no JCI Insight (2018)

Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes

Por Hisano, Yu, Kono, Mari, Cartier, Andreane, Engelbrecht, Eric, Kano, Kuniyuki, Kawakami, Kouki, Xiong, Yanbao, Piao, Wenji, Galvani, Sylvain, Yanagida, Keisuke, Kuo, Andrew, Ono, Yuki, Ishida, Satoru, Aoki, Junken, Proia, Richard L., Bromberg, Jonathan S., Inoue, Asuka, Hla, Timothy
Publicado no J Exp Med (2019)

S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress–dependent VEGF-C signaling

Por Geng, Xin, Yanagida, Keisuke, Akwii, Racheal G., Choi, Dongwon, Chen, Lijuan, Ho, YenChun, Cha, Boksik, Mahamud, Md. Riaj, Berman de Ruiz, Karen, Ichise, Hirotake, Chen, Hong, Wythe, Joshua D., Mikelis, Constantinos M., Hla, Timothy, Srinivasan, R. Sathish
Publicado no JCI Insight (2020)

An engineered S1P chaperone attenuates hypertension and ischemic injury

Por Swendeman, Steven L., Xiong, Yuquan, Cantalupo, Anna, Yuan, Hui, Burg, Nathalie, Hisano, Yu, Cartier, Andreane, Liu, Catherine H., Engelbrecht, Eric, Blaho, Victoria, Zhang, Yi, Yanagida, Keisuke, Galvani, Sylvain, Obinata, Hideru, Salmon, Jane E., Sanchez, Teresa, Di Lorenzo, Annarita, Hla, Timothy
Publicado no Sci Signal (2017)