Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids

Polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and arachidonic acid (ARA), play fundamental roles in mammalian physiology. Although PUFA imbalance causes various disorders, mechanisms of the regulation of their systemic levels are poorly understood. Here, we report that hepa...

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Foilsithe in:iScience
Main Authors: Hishikawa, Daisuke, Yanagida, Keisuke, Nagata, Katsuyuki, Kanatani, Ayumi, Iizuka, Yoshiko, Hamano, Fumie, Yasuda, Megumi, Okamura, Tadashi, Shindou, Hideo, Shimizu, Takao
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481256/
https://ncbi.nlm.nih.gov/pubmed/32891885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101495
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