An engineered S1P chaperone attenuates hypertension and ischemic injury

Endothelial dysfunction, a hallmark of vascular disease, is restored by plasma high-density lipoprotein (HDL). However, a generalized increase in HDL abundance is not beneficial, suggesting that specific HDL species mediate protective effects. Apolipoprotein M–containing HDL (ApoM(+)HDL), which carr...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Swendeman, Steven L., Xiong, Yuquan, Cantalupo, Anna, Yuan, Hui, Burg, Nathalie, Hisano, Yu, Cartier, Andreane, Liu, Catherine H., Engelbrecht, Eric, Blaho, Victoria, Zhang, Yi, Yanagida, Keisuke, Galvani, Sylvain, Obinata, Hideru, Salmon, Jane E., Sanchez, Teresa, Di Lorenzo, Annarita, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680089/
https://ncbi.nlm.nih.gov/pubmed/28811382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aal2722
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