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Sphingosine 1-phosphate in coagulation and inflammation

Sphingosine 1-phosphate (S1P) is a lipid mediator produced from sphingomyelin by the sequential enzymatic actions of sphingomyelinase, ceramidase, and sphingosine kinase. Five subtypes of cell surface G-protein-coupled receptors, S1P(1–5), mediate the actions of S1P in various organs systems, most n...

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Detalhes bibliográficos
Main Authors: Obinata, Hideru, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237867/
https://ncbi.nlm.nih.gov/pubmed/21805322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00281-011-0287-3
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