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Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient

Vertebrates are endowed with a closed circulatory system, the evolution of which required novel structural and regulatory changes. Furthermore, immune cell trafficking paradigms adapted to the barriers imposed by the closed circulatory system. How did such changes occur mechanistically? We propose t...

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Detalhes bibliográficos
Publicado no:Annu Rev Physiol
Main Authors: Yanagida, Keisuke, Hla, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500220/
https://ncbi.nlm.nih.gov/pubmed/27813829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021014-071635
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