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Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient

Vertebrates are endowed with a closed circulatory system, the evolution of which required novel structural and regulatory changes. Furthermore, immune cell trafficking paradigms adapted to the barriers imposed by the closed circulatory system. How did such changes occur mechanistically? We propose t...

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Vydáno v:Annu Rev Physiol
Hlavní autoři: Yanagida, Keisuke, Hla, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500220/
https://ncbi.nlm.nih.gov/pubmed/27813829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-021014-071635
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