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Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

Pancreatic cancer is highly metastatic and has a poor prognosis. However, there is no established treatment for pancreatic cancer. Lysophosphatidic acid (LPA) has been shown to be present in effluents of cancers and involved in migration and proliferation in a variety of cancer cells, including panc...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Komachi, Mayumi, Sato, Koichi, Tobo, Masayuki, Mogi, Chihiro, Yamada, Takayuki, Ohta, Hideo, Tomura, Hideaki, Kimura, Takao, Im, Dong‐Soon, Yanagida, Keisuke, Ishii, Satoshi, Takeyoshi, Izumi, Okajima, Fumikazu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685076/
https://ncbi.nlm.nih.gov/pubmed/22348348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2012.02246.x
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